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Chymase inhibition retards albuminuria in type 2 diabetes

Chymase released from mast cells produces pro‐fibrotic, inflammatory, and vasoconstrictor agents. Studies were performed to test the hypothesis that chronic chymase inhibition provides a renal protective effect in type 2 diabetes. Diabetic (db/db) and control mice (db/m) were chronically infused wit...

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Detalles Bibliográficos
Autores principales:	Bivona, Benjamin J., Takai, Shinji, Seth, Dale M., Satou, Ryousuke, Harrison‐Bernard, Lisa M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928241/ https://www.ncbi.nlm.nih.gov/pubmed/31872559 http://dx.doi.org/10.14814/phy2.14302

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