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Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy

Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are widely used for bowel cleansing before colonoscopy. This study aimed to investigate the pre-endoscopic predictive factors for inadequate preparation in subjects receiving low-volume PEG plus ascorbic acid. A prospective study was...

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Autores principales: Shin, Seung Yong, Ga, Kyeong Seon, Kim, In Young, Park, Yoo Mi, Jung, Da Hyun, Kim, Jie-Hyun, Youn, Young Hoon, Park, Hyojin, Park, Jae Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928254/
https://www.ncbi.nlm.nih.gov/pubmed/31873135
http://dx.doi.org/10.1038/s41598-019-56107-5
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author Shin, Seung Yong
Ga, Kyeong Seon
Kim, In Young
Park, Yoo Mi
Jung, Da Hyun
Kim, Jie-Hyun
Youn, Young Hoon
Park, Hyojin
Park, Jae Jun
author_facet Shin, Seung Yong
Ga, Kyeong Seon
Kim, In Young
Park, Yoo Mi
Jung, Da Hyun
Kim, Jie-Hyun
Youn, Young Hoon
Park, Hyojin
Park, Jae Jun
author_sort Shin, Seung Yong
collection PubMed
description Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are widely used for bowel cleansing before colonoscopy. This study aimed to investigate the pre-endoscopic predictive factors for inadequate preparation in subjects receiving low-volume PEG plus ascorbic acid. A prospective study was performed at Gangnam Severance Hospital, Korea, from June 2016 to December 2016. All participants received low-volume PEG plus ascorbic acid solutions for outpatient colonoscopy. The split-dose bowel preparation was administered in subject with morning colonoscopy while same day bowel preparation was used for afternoon colonoscopy. 715 patients were enrolled (mean age 56.1 years, 54.4% male), of which 138 (19.3%) had an inadequate bowel preparation. In multivariable analysis, cirrhosis (OR 4.943, 95% CI 1.191–20.515), low (less than 70%) compliance for three-day low-residual diet (OR 2.165, 95% CI 1.333–3.515), brown liquid rectal effluent (compared with clear or semi-clear effluent) (OR 7.604, 95% CI, 1.760–32.857), and longer time interval (≥2 hours) between last defecation and colonoscopic examination (OR 1.841, 95% CI, 1.190–2.849) were found as an independent predictors for inadequate preparation. These predictive factors may be useful in guiding additional intervention to improve quality of bowel preparation.
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spelling pubmed-69282542019-12-27 Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy Shin, Seung Yong Ga, Kyeong Seon Kim, In Young Park, Yoo Mi Jung, Da Hyun Kim, Jie-Hyun Youn, Young Hoon Park, Hyojin Park, Jae Jun Sci Rep Article Low-volume polyethylene glycol (PEG) plus ascorbic acid solutions are widely used for bowel cleansing before colonoscopy. This study aimed to investigate the pre-endoscopic predictive factors for inadequate preparation in subjects receiving low-volume PEG plus ascorbic acid. A prospective study was performed at Gangnam Severance Hospital, Korea, from June 2016 to December 2016. All participants received low-volume PEG plus ascorbic acid solutions for outpatient colonoscopy. The split-dose bowel preparation was administered in subject with morning colonoscopy while same day bowel preparation was used for afternoon colonoscopy. 715 patients were enrolled (mean age 56.1 years, 54.4% male), of which 138 (19.3%) had an inadequate bowel preparation. In multivariable analysis, cirrhosis (OR 4.943, 95% CI 1.191–20.515), low (less than 70%) compliance for three-day low-residual diet (OR 2.165, 95% CI 1.333–3.515), brown liquid rectal effluent (compared with clear or semi-clear effluent) (OR 7.604, 95% CI, 1.760–32.857), and longer time interval (≥2 hours) between last defecation and colonoscopic examination (OR 1.841, 95% CI, 1.190–2.849) were found as an independent predictors for inadequate preparation. These predictive factors may be useful in guiding additional intervention to improve quality of bowel preparation. Nature Publishing Group UK 2019-12-23 /pmc/articles/PMC6928254/ /pubmed/31873135 http://dx.doi.org/10.1038/s41598-019-56107-5 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Shin, Seung Yong
Ga, Kyeong Seon
Kim, In Young
Park, Yoo Mi
Jung, Da Hyun
Kim, Jie-Hyun
Youn, Young Hoon
Park, Hyojin
Park, Jae Jun
Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title_full Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title_fullStr Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title_full_unstemmed Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title_short Predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (PEG) plus ascorbic acid for an outpatient colonoscopy
title_sort predictive factors for inadequate bowel preparation using low-volume polyethylene glycol (peg) plus ascorbic acid for an outpatient colonoscopy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928254/
https://www.ncbi.nlm.nih.gov/pubmed/31873135
http://dx.doi.org/10.1038/s41598-019-56107-5
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