Complex interrelationships between nitro-alkene-dependent inhibition of soluble epoxide hydrolase, inflammation and tumor growth

Nitro-oleate (10-nitro-octadec-9-enoic acid), which inhibits soluble epoxide hydrolase (sEH) by covalently adducting to C521, increases the abundance of epoxyeicosatrienoic acids (EETs) that can be health promoting, for example by lowering blood pressure or their anti-inflammatory actions. However,...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-Ju, Switzer, Christopher Harry, Kamynina, Alisa, Charles, Rebecca, Rudyk, Olena, Ng, Tony, Burgoyne, Joseph Robert, Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928308/
https://www.ncbi.nlm.nih.gov/pubmed/31926628
http://dx.doi.org/10.1016/j.redox.2019.101405

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