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miR-30-5p-mediated ferroptosis of trophoblasts is implicated in the pathogenesis of preeclampsia
Oxidative stress is a major cause of adverse outcomes in preeclampsia (PE). Ferroptosis, i.e. programmed cell death from iron-dependent lipid peroxidation, likely mediates PE pathogenesis. We evaluated specific markers for ferroptosis in normal and PE placental tissues, using in vitro (trophoblasts)...
Autores principales: | Zhang, Heng, He, Yue, Wang, Jian-xia, Chen, Ming-hua, Xu, Jian-juan, Jiang, Min-hui, Feng, Ya-ling, Gu, Yan-fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928320/ https://www.ncbi.nlm.nih.gov/pubmed/31926626 http://dx.doi.org/10.1016/j.redox.2019.101402 |
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