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Early pneumococcal clearance in mice induced by systemic immunization with recombinant BCG PspA-PdT prime and protein boost correlates with cellular and humoral immune response in bronchoalveolar fluids (BALF)

An effective immunological response in the lungs during a pneumococcal infection is a key factor to the bacteria clearance and prevention of sepsis. In order to develop broad-range pneumococcal vaccines several pneumococcal proteins and strong adjuvants have been investigated. Previously, we constru...

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Detalles Bibliográficos
Autores principales:	Goulart, Cibelly, Rodriguez, Dunia, Kanno, Alex I., Silva, José Lourenço S.C., Leite, Luciana C.C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Regular paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928339/ https://www.ncbi.nlm.nih.gov/pubmed/31891153 http://dx.doi.org/10.1016/j.jvacx.2019.100049

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