Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes

We herein report a 28-year-old woman with type 1 diabetes with an asymptomatic pontine lesion and diabetic amyotrophy. She had suffered from diabetes from 10 years old. Treatment in a hospital reduced the hemoglobin A1c level from 14.2% to 7.2% for approximately 2 months. She suffered from acute-ons...

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Autores principales: Shimizu, Yuri, Kozawa, Junji, Hayakawa, Tomoaki, Sakai, Yasuha, Kimura, Takekazu, Kitamura, Tetsuhiro, Murase, Sho, Tanaka, Hisashi, Maeda, Norikazu, Otsuki, Michio, Matsuoka, Takaaki, Mochizuki, Hideki, Iwahashi, Hiromi, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928506/
https://www.ncbi.nlm.nih.gov/pubmed/31391398
http://dx.doi.org/10.2169/internalmedicine.2835-19
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author Shimizu, Yuri
Kozawa, Junji
Hayakawa, Tomoaki
Sakai, Yasuha
Kimura, Takekazu
Kitamura, Tetsuhiro
Murase, Sho
Tanaka, Hisashi
Maeda, Norikazu
Otsuki, Michio
Matsuoka, Takaaki
Mochizuki, Hideki
Iwahashi, Hiromi
Shimomura, Iichiro
author_facet Shimizu, Yuri
Kozawa, Junji
Hayakawa, Tomoaki
Sakai, Yasuha
Kimura, Takekazu
Kitamura, Tetsuhiro
Murase, Sho
Tanaka, Hisashi
Maeda, Norikazu
Otsuki, Michio
Matsuoka, Takaaki
Mochizuki, Hideki
Iwahashi, Hiromi
Shimomura, Iichiro
author_sort Shimizu, Yuri
collection PubMed
description We herein report a 28-year-old woman with type 1 diabetes with an asymptomatic pontine lesion and diabetic amyotrophy. She had suffered from diabetes from 10 years old. Treatment in a hospital reduced the hemoglobin A1c level from 14.2% to 7.2% for approximately 2 months. She suffered from acute-onset pain and weakness of the lower limb muscles without central nervous system manifestations. Magnetic resonance imaging showed high-intensity lesions at the brainstem and lower limb muscles on T2-weighted images. These findings and symptoms gradually resolved. Rapid treatment of poor glycemic control might increase the risk of asymptomatic pontine lesions and diabetic amyotrophy.
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spelling pubmed-69285062019-12-26 Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes Shimizu, Yuri Kozawa, Junji Hayakawa, Tomoaki Sakai, Yasuha Kimura, Takekazu Kitamura, Tetsuhiro Murase, Sho Tanaka, Hisashi Maeda, Norikazu Otsuki, Michio Matsuoka, Takaaki Mochizuki, Hideki Iwahashi, Hiromi Shimomura, Iichiro Intern Med Case Report We herein report a 28-year-old woman with type 1 diabetes with an asymptomatic pontine lesion and diabetic amyotrophy. She had suffered from diabetes from 10 years old. Treatment in a hospital reduced the hemoglobin A1c level from 14.2% to 7.2% for approximately 2 months. She suffered from acute-onset pain and weakness of the lower limb muscles without central nervous system manifestations. Magnetic resonance imaging showed high-intensity lesions at the brainstem and lower limb muscles on T2-weighted images. These findings and symptoms gradually resolved. Rapid treatment of poor glycemic control might increase the risk of asymptomatic pontine lesions and diabetic amyotrophy. The Japanese Society of Internal Medicine 2019-08-06 2019-12-01 /pmc/articles/PMC6928506/ /pubmed/31391398 http://dx.doi.org/10.2169/internalmedicine.2835-19 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shimizu, Yuri
Kozawa, Junji
Hayakawa, Tomoaki
Sakai, Yasuha
Kimura, Takekazu
Kitamura, Tetsuhiro
Murase, Sho
Tanaka, Hisashi
Maeda, Norikazu
Otsuki, Michio
Matsuoka, Takaaki
Mochizuki, Hideki
Iwahashi, Hiromi
Shimomura, Iichiro
Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title_full Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title_fullStr Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title_full_unstemmed Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title_short Asymptomatic Pontine Lesion and Diabetic Amyotrophy after Rapid Improvement of Poor Glycemic Control in a Patient with Type 1 Diabetes
title_sort asymptomatic pontine lesion and diabetic amyotrophy after rapid improvement of poor glycemic control in a patient with type 1 diabetes
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928506/
https://www.ncbi.nlm.nih.gov/pubmed/31391398
http://dx.doi.org/10.2169/internalmedicine.2835-19
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