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Notch3 signalling and vascular remodelling in pulmonary arterial hypertension

Notch signalling is critically involved in vascular morphogenesis and function. Four Notch isoforms (Notch1–4) regulating diverse cellular processes have been identified. Of these, Notch3 is expressed almost exclusively in vascular smooth muscle cells (VSMCs), where it is critically involved in vasc...

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Detalles Bibliográficos
Autores principales:	Morris, Hannah E., Neves, Karla B., Montezano, Augusto C., MacLean, Margaret R., Touyz, Rhian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Cardiovascular System & Vascular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928565/ https://www.ncbi.nlm.nih.gov/pubmed/31868216 http://dx.doi.org/10.1042/CS20190835

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