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Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018

Background: The opioid epidemic in the United States has resulted in a significant increase in fentanyl-related overdoses nationwide since 2013. Because of an increased rate of fentanyl-related overdoses seen in Jefferson Parish, LA, the Jefferson Parish Coroner's Office (JPCO) hypothesized tha...

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Autores principales: Noto, Kayla, Troxclair, Dana, Williams, Melva, Conners, Ronda, Mathes, Erin, Bone, Mark, Cvitanovich, Gerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Division of Ochsner Clinic Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928666/
https://www.ncbi.nlm.nih.gov/pubmed/31903054
http://dx.doi.org/10.31486/toj.19.0039
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author Noto, Kayla
Troxclair, Dana
Williams, Melva
Conners, Ronda
Mathes, Erin
Bone, Mark
Cvitanovich, Gerry
author_facet Noto, Kayla
Troxclair, Dana
Williams, Melva
Conners, Ronda
Mathes, Erin
Bone, Mark
Cvitanovich, Gerry
author_sort Noto, Kayla
collection PubMed
description Background: The opioid epidemic in the United States has resulted in a significant increase in fentanyl-related overdoses nationwide since 2013. Because of an increased rate of fentanyl-related overdoses seen in Jefferson Parish, LA, the Jefferson Parish Coroner's Office (JPCO) hypothesized that the opioid epidemic, specifically related to fentanyl, had reached this region. To test this hypothesis, JPCO analyzed fentanyl overdose deaths to determine if the deaths had increased during a 6-year period and if the change met the definition of an epidemic. Methods: In the toxicology laboratory at JPCO, enzyme-linked immunosorbent assay screening and gas chromatography/mass spectrometry are used in-house to determine the presence of drugs. Drug-positive samples are sent to National Medical Services (NMS) Labs to quantify the analyte concentration in each sample. Data for each decedent were extracted from the Medicolegal Death Investigation Log (MDILog) database for the years 2013 through 2018. Results: A slow increase in fentanyl-related deaths during the first 3 years of the study period was followed by a near doubling of cases in 2016, a tripling of cases in 2017, and a 6-fold increase in incidence in 2018. During the 6-year study period, fentanyl-related deaths increased from 6 in 2013, to 8 in 2014, to 14 in 2015. Twenty-five deaths in 2016 spiked to 66 in 2017 and increased to 78 fentanyl-related overdose deaths in 2018. The percentage of fentanyl-related overdose deaths increased from 4% of all drug deaths in 2013 to 45% in 2018. Conclusion: The data validate the hypothesis that the fentanyl epidemic has affected Jefferson Parish in southeast Louisiana.
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spelling pubmed-69286662020-01-03 Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018 Noto, Kayla Troxclair, Dana Williams, Melva Conners, Ronda Mathes, Erin Bone, Mark Cvitanovich, Gerry Ochsner J Original Research Background: The opioid epidemic in the United States has resulted in a significant increase in fentanyl-related overdoses nationwide since 2013. Because of an increased rate of fentanyl-related overdoses seen in Jefferson Parish, LA, the Jefferson Parish Coroner's Office (JPCO) hypothesized that the opioid epidemic, specifically related to fentanyl, had reached this region. To test this hypothesis, JPCO analyzed fentanyl overdose deaths to determine if the deaths had increased during a 6-year period and if the change met the definition of an epidemic. Methods: In the toxicology laboratory at JPCO, enzyme-linked immunosorbent assay screening and gas chromatography/mass spectrometry are used in-house to determine the presence of drugs. Drug-positive samples are sent to National Medical Services (NMS) Labs to quantify the analyte concentration in each sample. Data for each decedent were extracted from the Medicolegal Death Investigation Log (MDILog) database for the years 2013 through 2018. Results: A slow increase in fentanyl-related deaths during the first 3 years of the study period was followed by a near doubling of cases in 2016, a tripling of cases in 2017, and a 6-fold increase in incidence in 2018. During the 6-year study period, fentanyl-related deaths increased from 6 in 2013, to 8 in 2014, to 14 in 2015. Twenty-five deaths in 2016 spiked to 66 in 2017 and increased to 78 fentanyl-related overdose deaths in 2018. The percentage of fentanyl-related overdose deaths increased from 4% of all drug deaths in 2013 to 45% in 2018. Conclusion: The data validate the hypothesis that the fentanyl epidemic has affected Jefferson Parish in southeast Louisiana. Academic Division of Ochsner Clinic Foundation 2019 2019 /pmc/articles/PMC6928666/ /pubmed/31903054 http://dx.doi.org/10.31486/toj.19.0039 Text en ©2019 by the author(s); Creative Commons Attribution License (CC BY) http://creativecommons.org/licenses/by/4.0/legalcode ©2019 by the author(s); licensee Ochsner Journal, Ochsner Clinic Foundation, New Orleans, LA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (creativecommons.org/licenses/by/4.0/legalcode) that permits unrestricted use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Research
Noto, Kayla
Troxclair, Dana
Williams, Melva
Conners, Ronda
Mathes, Erin
Bone, Mark
Cvitanovich, Gerry
Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title_full Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title_fullStr Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title_full_unstemmed Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title_short Surge in Fentanyl Toxicity Deaths in Jefferson Parish, LA, 2013-2018
title_sort surge in fentanyl toxicity deaths in jefferson parish, la, 2013-2018
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928666/
https://www.ncbi.nlm.nih.gov/pubmed/31903054
http://dx.doi.org/10.31486/toj.19.0039
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