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Autophagy in the Central Nervous System and Effects of Chloroquine in Mucopolysaccharidosis Type II Mice

Mucopolysaccharidosis type II (MPS II) is a rare lysosomal storage disease (LSD) involving a genetic error in iduronic acid-2-sulfatase (IDS) metabolism that leads to accumulation of glycosaminoglycans within intracellular lysosomes. The primary treatment for MPS II, enzyme replacement therapy, is n...

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Detalles Bibliográficos
Autores principales: Maeda, Mitsuyo, Seto, Toshiyuki, Kadono, Chiho, Morimoto, Hideto, Kida, Sachiho, Suga, Mitsuo, Nakamura, Motohiro, Kataoka, Yosky, Hamazaki, Takashi, Shintaku, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928680/
https://www.ncbi.nlm.nih.gov/pubmed/31757021
http://dx.doi.org/10.3390/ijms20235829

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