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Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests

Increasingly more patients exposed to radiation from computed axial tomography (CT) will have a greater risk of developing tumors or cancer that are caused by cell mutation in the future. A minor dose level would decrease the number of these possible cases. However, this framework can result in medi...

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Autores principales: Garcia-Sanchez, Antonio-Javier, Garcia Angosto, Enrique, Llor, Jose Luis, Serna Berna, Alfredo, Ramos, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928694/
https://www.ncbi.nlm.nih.gov/pubmed/31766708
http://dx.doi.org/10.3390/s19235116
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author Garcia-Sanchez, Antonio-Javier
Garcia Angosto, Enrique
Llor, Jose Luis
Serna Berna, Alfredo
Ramos, David
author_facet Garcia-Sanchez, Antonio-Javier
Garcia Angosto, Enrique
Llor, Jose Luis
Serna Berna, Alfredo
Ramos, David
author_sort Garcia-Sanchez, Antonio-Javier
collection PubMed
description Increasingly more patients exposed to radiation from computed axial tomography (CT) will have a greater risk of developing tumors or cancer that are caused by cell mutation in the future. A minor dose level would decrease the number of these possible cases. However, this framework can result in medical specialists (radiologists) not being able to detect anomalies or lesions. This work explores a way of addressing these concerns, achieving the reduction of unnecessary radiation without compromising the diagnosis. We contribute with a novel methodology in the CT area to predict the precise radiation that a patient should be given to accomplish this goal. Specifically, from a real dataset composed of the dose data of over fifty thousand patients that have been classified into standardized protocols (skull, abdomen, thorax, pelvis, etc.), we eliminate atypical information (outliers), to later generate regression curves employing diverse well-known Machine Learning techniques. As a result, we have chosen the best analytical technique per protocol; a selection that was thoroughly carried out according to traditional dosimetry parameters to accurately quantify the dose level that the radiologist should apply in each CT test.
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spelling pubmed-69286942019-12-26 Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests Garcia-Sanchez, Antonio-Javier Garcia Angosto, Enrique Llor, Jose Luis Serna Berna, Alfredo Ramos, David Sensors (Basel) Article Increasingly more patients exposed to radiation from computed axial tomography (CT) will have a greater risk of developing tumors or cancer that are caused by cell mutation in the future. A minor dose level would decrease the number of these possible cases. However, this framework can result in medical specialists (radiologists) not being able to detect anomalies or lesions. This work explores a way of addressing these concerns, achieving the reduction of unnecessary radiation without compromising the diagnosis. We contribute with a novel methodology in the CT area to predict the precise radiation that a patient should be given to accomplish this goal. Specifically, from a real dataset composed of the dose data of over fifty thousand patients that have been classified into standardized protocols (skull, abdomen, thorax, pelvis, etc.), we eliminate atypical information (outliers), to later generate regression curves employing diverse well-known Machine Learning techniques. As a result, we have chosen the best analytical technique per protocol; a selection that was thoroughly carried out according to traditional dosimetry parameters to accurately quantify the dose level that the radiologist should apply in each CT test. MDPI 2019-11-22 /pmc/articles/PMC6928694/ /pubmed/31766708 http://dx.doi.org/10.3390/s19235116 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garcia-Sanchez, Antonio-Javier
Garcia Angosto, Enrique
Llor, Jose Luis
Serna Berna, Alfredo
Ramos, David
Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title_full Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title_fullStr Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title_full_unstemmed Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title_short Machine Learning Techniques Applied to Dose Prediction in Computed Tomography Tests
title_sort machine learning techniques applied to dose prediction in computed tomography tests
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928694/
https://www.ncbi.nlm.nih.gov/pubmed/31766708
http://dx.doi.org/10.3390/s19235116
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