3’-O-Methylorobol Inhibits the Voltage-Gated Sodium Channel Nav1.7 with Anti-Itch Efficacy in A Histamine-Dependent Itch Mouse Model

An itch is a clinical complication that affects millions of patients. However, few treatment options are available. The voltage-gated sodium channel Nav1.7 is predominantly expressed in peripheral sensory neurons and is responsible for the rising phase of action potentials, thereby mediating nocicep...

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Detalles Bibliográficos
Autores principales: Zhang, Fan, Wu, Ying, Xue, Shuwen, Wang, Shuangyan, Zhang, Chunlei, Cao, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928743/
https://www.ncbi.nlm.nih.gov/pubmed/31805638
http://dx.doi.org/10.3390/ijms20236058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928743/
https://www.ncbi.nlm.nih.gov/pubmed/31805638
http://dx.doi.org/10.3390/ijms20236058

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