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The Dual Interactions of p53 with MDM2 and p300: Implications for the Design of MDM2 Inhibitors
Proteins that limit the activity of the tumour suppressor protein p53 are increasingly being targeted for inhibition in a variety of cancers. In addition to the development of small molecules, there has been interest in developing constrained (stapled) peptide inhibitors. A stapled peptide ALRN_6924...
Autores principales: | Kannan, Srinivasaraghavan, Partridge, Anthony W., Lane, David P., Verma, Chandra S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928821/ https://www.ncbi.nlm.nih.gov/pubmed/31795143 http://dx.doi.org/10.3390/ijms20235996 |
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