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Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines

We propose a novel platform for detecting as well as measuring the size of individual droplets in microfluidic channels using microstrip transmission lines. The most outstanding feature of our platform is that, as opposed to previous related works, its design allows for the droplet to flow in a micr...

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Detalles Bibliográficos
Autores principales: de Novais Schianti, Juliana, L. C. Serrano, Ariana, Orquiza de Carvalho, Daniel, A. Penchel, Rafael, Mota Pinheiro, Julio, Gongora-Rubio, Mario R., Pamplona Rehder, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928822/
https://www.ncbi.nlm.nih.gov/pubmed/31795086
http://dx.doi.org/10.3390/s19235216
Descripción
Sumario:We propose a novel platform for detecting as well as measuring the size of individual droplets in microfluidic channels using microstrip transmission lines. The most outstanding feature of our platform is that, as opposed to previous related works, its design allows for the droplet to flow in a microfluidic channel fabricated between the top strip and the ground plane of a microstrip transmission line. This provides enhanced interaction of the electromagnetic field with the detected droplets. The proposed design allows us to measure droplet size directly from the phase of the microwave signal, without the need for a resonator. The platform is based on low temperature co-fired ceramic (LTCC), which makes it more compatible with Radiofrequency (RF) and microwave technology than platforms used in previous works. With this platform, we are able to measure droplets as small as 150 µm in radius. It is worth pointing out that our device could also be used for detection, counting and measurement of other microscopic objects.