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Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines

We propose a novel platform for detecting as well as measuring the size of individual droplets in microfluidic channels using microstrip transmission lines. The most outstanding feature of our platform is that, as opposed to previous related works, its design allows for the droplet to flow in a micr...

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Autores principales: de Novais Schianti, Juliana, L. C. Serrano, Ariana, Orquiza de Carvalho, Daniel, A. Penchel, Rafael, Mota Pinheiro, Julio, Gongora-Rubio, Mario R., Pamplona Rehder, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928822/
https://www.ncbi.nlm.nih.gov/pubmed/31795086
http://dx.doi.org/10.3390/s19235216
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author de Novais Schianti, Juliana
L. C. Serrano, Ariana
Orquiza de Carvalho, Daniel
A. Penchel, Rafael
Mota Pinheiro, Julio
Gongora-Rubio, Mario R.
Pamplona Rehder, Gustavo
author_facet de Novais Schianti, Juliana
L. C. Serrano, Ariana
Orquiza de Carvalho, Daniel
A. Penchel, Rafael
Mota Pinheiro, Julio
Gongora-Rubio, Mario R.
Pamplona Rehder, Gustavo
author_sort de Novais Schianti, Juliana
collection PubMed
description We propose a novel platform for detecting as well as measuring the size of individual droplets in microfluidic channels using microstrip transmission lines. The most outstanding feature of our platform is that, as opposed to previous related works, its design allows for the droplet to flow in a microfluidic channel fabricated between the top strip and the ground plane of a microstrip transmission line. This provides enhanced interaction of the electromagnetic field with the detected droplets. The proposed design allows us to measure droplet size directly from the phase of the microwave signal, without the need for a resonator. The platform is based on low temperature co-fired ceramic (LTCC), which makes it more compatible with Radiofrequency (RF) and microwave technology than platforms used in previous works. With this platform, we are able to measure droplets as small as 150 µm in radius. It is worth pointing out that our device could also be used for detection, counting and measurement of other microscopic objects.
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spelling pubmed-69288222019-12-26 Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines de Novais Schianti, Juliana L. C. Serrano, Ariana Orquiza de Carvalho, Daniel A. Penchel, Rafael Mota Pinheiro, Julio Gongora-Rubio, Mario R. Pamplona Rehder, Gustavo Sensors (Basel) Article We propose a novel platform for detecting as well as measuring the size of individual droplets in microfluidic channels using microstrip transmission lines. The most outstanding feature of our platform is that, as opposed to previous related works, its design allows for the droplet to flow in a microfluidic channel fabricated between the top strip and the ground plane of a microstrip transmission line. This provides enhanced interaction of the electromagnetic field with the detected droplets. The proposed design allows us to measure droplet size directly from the phase of the microwave signal, without the need for a resonator. The platform is based on low temperature co-fired ceramic (LTCC), which makes it more compatible with Radiofrequency (RF) and microwave technology than platforms used in previous works. With this platform, we are able to measure droplets as small as 150 µm in radius. It is worth pointing out that our device could also be used for detection, counting and measurement of other microscopic objects. MDPI 2019-11-28 /pmc/articles/PMC6928822/ /pubmed/31795086 http://dx.doi.org/10.3390/s19235216 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Novais Schianti, Juliana
L. C. Serrano, Ariana
Orquiza de Carvalho, Daniel
A. Penchel, Rafael
Mota Pinheiro, Julio
Gongora-Rubio, Mario R.
Pamplona Rehder, Gustavo
Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title_full Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title_fullStr Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title_full_unstemmed Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title_short Novel Platform for Droplet Detection and Size Measurement Using Microstrip Transmission Lines
title_sort novel platform for droplet detection and size measurement using microstrip transmission lines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928822/
https://www.ncbi.nlm.nih.gov/pubmed/31795086
http://dx.doi.org/10.3390/s19235216
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