Caspase-8 Regulates Endoplasmic Reticulum Stress-Induced Necroptosis Independent of the Apoptosis Pathway in Auditory Cells

The aim of this study is to elucidate the detailed mechanism of endoplasmic reticulum (ER) stress-induced auditory cell death based on the function of the initiator caspases and molecular complex of necroptosis. Here, we demonstrated that ER stress initiates not only caspase-9-dependent intrinsic ap...

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Detalles Bibliográficos
Autores principales: Kishino, Akihiro, Hayashi, Ken, Maeda, Miyoko, Jike, Toyoharu, Hidai, Chiaki, Nomura, Yasuyuki, Oshima, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928907/
https://www.ncbi.nlm.nih.gov/pubmed/31771290
http://dx.doi.org/10.3390/ijms20235896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928907/
https://www.ncbi.nlm.nih.gov/pubmed/31771290
http://dx.doi.org/10.3390/ijms20235896

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