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Different Forms of TFF2, A Lectin of the Human Gastric Mucus Barrier: In Vitro Binding Studies

Trefoil factor family 2 (TFF2) and the mucin MUC6 are co-secreted from human gastric and duodenal glands. TFF2 binds MUC6 as a lectin and is a constituent of the gastric mucus. Herein, we investigated human gastric extracts by FPLC and identified mainly high- but also low-molecular-mass forms of TFF...

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Detalles Bibliográficos
Autores principales: Heuer, Franziska, Stürmer, René, Heuer, Jörn, Kalinski, Thomas, Lemke, Antje, Meyer, Frank, Hoffmann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928932/
https://www.ncbi.nlm.nih.gov/pubmed/31771101
http://dx.doi.org/10.3390/ijms20235871