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Endomorphin-2- and Neurotensin- Based Chimeric Peptide Attenuates Airway Inflammation in Mouse Model of Nonallergic Asthma
We examined anti-inflammatory potency of hybrid peptide-PK20, composed of neurotensin (NT) and endomorphin-2 (EM-2) pharmacophores in a murine model of non-atopic asthma induced by skin sensitization with 2,4-dinitrofluorobenzene and intratracheal challenge of cognate hapten. Mice received intraperi...
Autores principales: | Russjan, Ewelina, Andrzejewski, Kryspin, Sulejczak, Dorota, Kleczkowska, Patrycja, Kaczyńska, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929018/ https://www.ncbi.nlm.nih.gov/pubmed/31779093 http://dx.doi.org/10.3390/ijms20235935 |
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