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Renal Tubular Glucagon-Like Peptide-1 Receptor Expression Is Increased in Early Sepsis but Reduced in Chronic Kidney Disease and Sepsis-Induced Kidney Injury

Acute kidney injury (AKI) is common in patients with sepsis and causes renal ischemia. Glucagon-like peptide-1 (GLP-1) protects the vascular system and the kidney, and GLP-1 receptor (GLP-1R) is expressed in the kidney. Renal GLP-1R activity is decreased in chronic kidney disease (CKD), but is incre...

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Detalles Bibliográficos
Autores principales: Choi, Jae Hyun, Kim, Seung Jung, Kwon, Soon Kil, Kim, Hye-Young, Jeon, Hyunjung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929157/
https://www.ncbi.nlm.nih.gov/pubmed/31795376
http://dx.doi.org/10.3390/ijms20236024