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The Role of C-X-C Chemokine Receptor Type 4 (CXCR4) in Cell Adherence and Spheroid Formation of Human Ewing’s Sarcoma Cells under Simulated Microgravity

We studied the behavior of Ewing’s Sarcoma cells of the line A673 under simulated microgravity (s-µg). These cells express two prominent markers—the oncogene EWS/FLI1 and the chemokine receptor CXCR4, which is used as a target of treatment in several types of cancer. The cells were exposed to s-µg i...

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Detalles Bibliográficos
Autores principales: Romswinkel, Alexander, Infanger, Manfred, Dietz, Carlo, Strube, Florian, Kraus, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929163/
https://www.ncbi.nlm.nih.gov/pubmed/31810195
http://dx.doi.org/10.3390/ijms20236073

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