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Model Optimization and In Silico Analysis of Potential Dipeptidyl Peptidase IV Antagonists from GC-MS Identified Compounds in Nauclea latifolia Leaf Extracts

Dipeptidyl peptidase IV (DPP-IV) is a pharmacotherapeutic target in type 2 diabetes. Inhibitors of this enzyme constitute a new class of drugs used in the treatment and management of type 2 diabetes. In this study, phytocompounds in Nauclea latifolia (NL) leaf extracts, identified using gas chromato...

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Detalles Bibliográficos
Autores principales: Iheagwam, Franklyn Nonso, Ogunlana, Olubanke Olujoke, Chinedu, Shalom Nwodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929178/
https://www.ncbi.nlm.nih.gov/pubmed/31775302
http://dx.doi.org/10.3390/ijms20235913

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