The Role of Immune Cells and Cytokines in Intestinal Wound Healing

Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells)...

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Detalles Bibliográficos
Autores principales: Xue, Xiang, Falcon, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929186/
https://www.ncbi.nlm.nih.gov/pubmed/31816903
http://dx.doi.org/10.3390/ijms20236097
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author Xue, Xiang
Falcon, Daniel M.
author_facet Xue, Xiang
Falcon, Daniel M.
author_sort Xue, Xiang
collection PubMed
description Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells) and four cytokines (interleukin-10, tumor necrosis factor alpha, interleukin-6, and interleukin-22) to the wound repair process in the gut. Better understanding of these immune factors will be important for developing novel targeted therapy.
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spelling pubmed-69291862019-12-26 The Role of Immune Cells and Cytokines in Intestinal Wound Healing Xue, Xiang Falcon, Daniel M. Int J Mol Sci Review Intestinal wound healing is a complicated process that not only involves epithelial cells but also immune cells. In this brief review, we will focus on discussing the contribution and regulation of four major immune cell types (neutrophils, macrophages, regulatory T cells, and innate lymphoid cells) and four cytokines (interleukin-10, tumor necrosis factor alpha, interleukin-6, and interleukin-22) to the wound repair process in the gut. Better understanding of these immune factors will be important for developing novel targeted therapy. MDPI 2019-12-03 /pmc/articles/PMC6929186/ /pubmed/31816903 http://dx.doi.org/10.3390/ijms20236097 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Xue, Xiang
Falcon, Daniel M.
The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title_full The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title_fullStr The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title_full_unstemmed The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title_short The Role of Immune Cells and Cytokines in Intestinal Wound Healing
title_sort role of immune cells and cytokines in intestinal wound healing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929186/
https://www.ncbi.nlm.nih.gov/pubmed/31816903
http://dx.doi.org/10.3390/ijms20236097
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