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Psychopathology and personality factors in first-degree relatives of patients with schizophrenia

BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. Th...

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Autores principales: Verma, Nitisha, Sinha, Deoraj, Dave, Malay, Kamath, Ravindra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929218/
https://www.ncbi.nlm.nih.gov/pubmed/31879455
http://dx.doi.org/10.4103/ipj.ipj_54_17
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author Verma, Nitisha
Sinha, Deoraj
Dave, Malay
Kamath, Ravindra M.
author_facet Verma, Nitisha
Sinha, Deoraj
Dave, Malay
Kamath, Ravindra M.
author_sort Verma, Nitisha
collection PubMed
description BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. This study was planned to assess psychopathology and personality factors in first degree relatives of patients with schizophrenia and to evaluate any relation between them. MATERIALS AND METHODS: This was a cross-sectional study conducted at psychiatry out- and in-patient clinic at a tertiary care teaching hospital. One hundred and fifty patients who were first-degree relatives of patients diagnosed with schizophrenia on the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition were enrolled in this study. Psychopathology was assessed on “Symptom Checklist 90-Revised.” “Big Five Inventory” (BFI) was used to study the personality factors. The two variables were compared to look for any relation between them. RESULTS: Eighty-two of 150 (54.67%) first-degree relatives were diagnosed to have significant psychopathology. Among them, 42 (i.e., 58.5%) had either somatization or depression. Those relatives who had psychopathology scored higher on neuroticism (P = 3.51E-04) and lower on agreeableness (P = 0.029) domains of BFI. CONCLUSION: Relatives of patients with schizophrenia should be screened for psychopathology regularly, also relation between personality and psychopathology needs to be explored further.
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spelling pubmed-69292182019-12-26 Psychopathology and personality factors in first-degree relatives of patients with schizophrenia Verma, Nitisha Sinha, Deoraj Dave, Malay Kamath, Ravindra M. Ind Psychiatry J Original Article BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. This study was planned to assess psychopathology and personality factors in first degree relatives of patients with schizophrenia and to evaluate any relation between them. MATERIALS AND METHODS: This was a cross-sectional study conducted at psychiatry out- and in-patient clinic at a tertiary care teaching hospital. One hundred and fifty patients who were first-degree relatives of patients diagnosed with schizophrenia on the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition were enrolled in this study. Psychopathology was assessed on “Symptom Checklist 90-Revised.” “Big Five Inventory” (BFI) was used to study the personality factors. The two variables were compared to look for any relation between them. RESULTS: Eighty-two of 150 (54.67%) first-degree relatives were diagnosed to have significant psychopathology. Among them, 42 (i.e., 58.5%) had either somatization or depression. Those relatives who had psychopathology scored higher on neuroticism (P = 3.51E-04) and lower on agreeableness (P = 0.029) domains of BFI. CONCLUSION: Relatives of patients with schizophrenia should be screened for psychopathology regularly, also relation between personality and psychopathology needs to be explored further. Wolters Kluwer - Medknow 2019 2019-12-11 /pmc/articles/PMC6929218/ /pubmed/31879455 http://dx.doi.org/10.4103/ipj.ipj_54_17 Text en Copyright: © 2019 Industrial Psychiatry Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Verma, Nitisha
Sinha, Deoraj
Dave, Malay
Kamath, Ravindra M.
Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title_full Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title_fullStr Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title_full_unstemmed Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title_short Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
title_sort psychopathology and personality factors in first-degree relatives of patients with schizophrenia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929218/
https://www.ncbi.nlm.nih.gov/pubmed/31879455
http://dx.doi.org/10.4103/ipj.ipj_54_17
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