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Psychopathology and personality factors in first-degree relatives of patients with schizophrenia
BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. Th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929218/ https://www.ncbi.nlm.nih.gov/pubmed/31879455 http://dx.doi.org/10.4103/ipj.ipj_54_17 |
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author | Verma, Nitisha Sinha, Deoraj Dave, Malay Kamath, Ravindra M. |
author_facet | Verma, Nitisha Sinha, Deoraj Dave, Malay Kamath, Ravindra M. |
author_sort | Verma, Nitisha |
collection | PubMed |
description | BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. This study was planned to assess psychopathology and personality factors in first degree relatives of patients with schizophrenia and to evaluate any relation between them. MATERIALS AND METHODS: This was a cross-sectional study conducted at psychiatry out- and in-patient clinic at a tertiary care teaching hospital. One hundred and fifty patients who were first-degree relatives of patients diagnosed with schizophrenia on the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition were enrolled in this study. Psychopathology was assessed on “Symptom Checklist 90-Revised.” “Big Five Inventory” (BFI) was used to study the personality factors. The two variables were compared to look for any relation between them. RESULTS: Eighty-two of 150 (54.67%) first-degree relatives were diagnosed to have significant psychopathology. Among them, 42 (i.e., 58.5%) had either somatization or depression. Those relatives who had psychopathology scored higher on neuroticism (P = 3.51E-04) and lower on agreeableness (P = 0.029) domains of BFI. CONCLUSION: Relatives of patients with schizophrenia should be screened for psychopathology regularly, also relation between personality and psychopathology needs to be explored further. |
format | Online Article Text |
id | pubmed-6929218 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-69292182019-12-26 Psychopathology and personality factors in first-degree relatives of patients with schizophrenia Verma, Nitisha Sinha, Deoraj Dave, Malay Kamath, Ravindra M. Ind Psychiatry J Original Article BACKGROUND: Schizophrenia is a chronic mental illness which has far-reaching consequences not only on patients but also on relatives. These relatives are at an increased risk for developing schizophrenia, depression, and substance dependence. Psychopathology may be related to personality factors. This study was planned to assess psychopathology and personality factors in first degree relatives of patients with schizophrenia and to evaluate any relation between them. MATERIALS AND METHODS: This was a cross-sectional study conducted at psychiatry out- and in-patient clinic at a tertiary care teaching hospital. One hundred and fifty patients who were first-degree relatives of patients diagnosed with schizophrenia on the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition were enrolled in this study. Psychopathology was assessed on “Symptom Checklist 90-Revised.” “Big Five Inventory” (BFI) was used to study the personality factors. The two variables were compared to look for any relation between them. RESULTS: Eighty-two of 150 (54.67%) first-degree relatives were diagnosed to have significant psychopathology. Among them, 42 (i.e., 58.5%) had either somatization or depression. Those relatives who had psychopathology scored higher on neuroticism (P = 3.51E-04) and lower on agreeableness (P = 0.029) domains of BFI. CONCLUSION: Relatives of patients with schizophrenia should be screened for psychopathology regularly, also relation between personality and psychopathology needs to be explored further. Wolters Kluwer - Medknow 2019 2019-12-11 /pmc/articles/PMC6929218/ /pubmed/31879455 http://dx.doi.org/10.4103/ipj.ipj_54_17 Text en Copyright: © 2019 Industrial Psychiatry Journal http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Verma, Nitisha Sinha, Deoraj Dave, Malay Kamath, Ravindra M. Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title | Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title_full | Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title_fullStr | Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title_full_unstemmed | Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title_short | Psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
title_sort | psychopathology and personality factors in first-degree relatives of patients with schizophrenia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929218/ https://www.ncbi.nlm.nih.gov/pubmed/31879455 http://dx.doi.org/10.4103/ipj.ipj_54_17 |
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