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Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor

Leydig cell tumors (LCTs) are rare testicular tumors that may be a cause of precocious puberty in males. We present a 5-year-old boy with a five-month history of pubic hair appearance associated with an increase in penile length, scrotal hyperpigmentation, change in body odor, and bone age advanced...

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Autores principales: Alagha, Eid, Kafi, Shahd E, Shazly, Mohamed Abdelmaksoud, Al-Agha, Abdulmoein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929247/
https://www.ncbi.nlm.nih.gov/pubmed/31893190
http://dx.doi.org/10.7759/cureus.6441
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author Alagha, Eid
Kafi, Shahd E
Shazly, Mohamed Abdelmaksoud
Al-Agha, Abdulmoein
author_facet Alagha, Eid
Kafi, Shahd E
Shazly, Mohamed Abdelmaksoud
Al-Agha, Abdulmoein
author_sort Alagha, Eid
collection PubMed
description Leydig cell tumors (LCTs) are rare testicular tumors that may be a cause of precocious puberty in males. We present a 5-year-old boy with a five-month history of pubic hair appearance associated with an increase in penile length, scrotal hyperpigmentation, change in body odor, and bone age advanced by two years. His hormonal tests revealed the diagnosis of pseudo precocious puberty. Testicular ultrasound showed a unilateral right testicular enlargement. Surgery was performed to remove the mass. Histopathology confirmed the diagnosis of LCT. This case report highlights the importance of consideration of testicular tumors in boys with precocious puberty.
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spelling pubmed-69292472019-12-31 Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor Alagha, Eid Kafi, Shahd E Shazly, Mohamed Abdelmaksoud Al-Agha, Abdulmoein Cureus Endocrinology/Diabetes/Metabolism Leydig cell tumors (LCTs) are rare testicular tumors that may be a cause of precocious puberty in males. We present a 5-year-old boy with a five-month history of pubic hair appearance associated with an increase in penile length, scrotal hyperpigmentation, change in body odor, and bone age advanced by two years. His hormonal tests revealed the diagnosis of pseudo precocious puberty. Testicular ultrasound showed a unilateral right testicular enlargement. Surgery was performed to remove the mass. Histopathology confirmed the diagnosis of LCT. This case report highlights the importance of consideration of testicular tumors in boys with precocious puberty. Cureus 2019-12-22 /pmc/articles/PMC6929247/ /pubmed/31893190 http://dx.doi.org/10.7759/cureus.6441 Text en Copyright © 2019, Alagha et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Alagha, Eid
Kafi, Shahd E
Shazly, Mohamed Abdelmaksoud
Al-Agha, Abdulmoein
Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title_full Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title_fullStr Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title_full_unstemmed Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title_short Precocious Puberty Associated with Testicular Hormone-secreting Leydig Cell Tumor
title_sort precocious puberty associated with testicular hormone-secreting leydig cell tumor
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929247/
https://www.ncbi.nlm.nih.gov/pubmed/31893190
http://dx.doi.org/10.7759/cureus.6441
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