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Identification of highly conserved, serotype-specific dengue virus sequences: implications for vaccine design
BACKGROUND: The sequence diversity of dengue virus (DENV) is one of the challenges in developing an effective vaccine against the virus. Highly conserved, serotype-specific (HCSS), immune-relevant DENV sequences are attractive candidates for vaccine design, and represent an alternative to the approa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929274/ https://www.ncbi.nlm.nih.gov/pubmed/31874646 http://dx.doi.org/10.1186/s12864-019-6311-z |