In vitro activity of 1H-phenalen-1-one derivatives against Leishmania spp. and evidence of programmed cell death

BACKGROUND: The in vitro activity against Leishmania spp. of a novel group of compounds, phenalenone derivatives, is described in this study. Previous studies have shown that some phenalenones present leishmanicidal activity, and induce a decrease in the mitochondrial membrane potential in L. amazon...

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Detalles Bibliográficos
Autores principales: López-Arencibia, Atteneri, Reyes-Batlle, María, Freijo, Mónica B., Sifaoui, Ines, Bethencourt-Estrella, Carlos J., Rizo-Liendo, Aitor, Chiboub, Olfa, McNaughton-Smith, Grant, Lorenzo-Morales, Jacob, Abad-Grillo, Teresa, Piñero, José E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929359/
https://www.ncbi.nlm.nih.gov/pubmed/31870406
http://dx.doi.org/10.1186/s13071-019-3854-4

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