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Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study

BACKGROUND: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-...

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Autores principales: Galmes-Panades, Aina M., Varela-Mato, Veronica, Konieczna, Jadwiga, Wärnberg, Julia, Martínez-González, Miguel Ángel, Salas-Salvadó, Jordi, Corella, Dolores, Schröder, Helmut, Vioque, Jesús, Alonso-Gómez, Ángel M., Martínez, J. Alfredo, Serra-Majem, Luís, Estruch, Ramon, Tinahones, Francisco J., Lapetra, José, Pintó, Xavier, Tur, Josep A., Garcia-Rios, Antonio, Riquelme-Gallego, Blanca, Gaforio, José Juan, Matía-Martín, Pilar, Daimiel, Lidia, Micó Pérez, Rafael Manuel, Vidal, Josep, Vázquez, Clotilde, Ros, Emilio, Garcia-Arellano, Ana, Díaz-López, Andrés, Asensio, Eva M., Castañer, Olga, Fiol, Francisca, Mira-Castejón, Luis Alfredo, Moreno Rodríguez, Anai, Benavente- Marín, Juan Carlos, Abete, Itziar, Tomaino, Laura, Casas, Rosa, Barón López, F. Javier, Fernández-García, José Carlos, Santos-Lozano, José Manuel, Galera, Ana, Mascaró, Catalina M., Razquin, Cristina, Papandreou, Christopher, Portoles, Olga, Pérez-Vega, Karla Alejandra, Fiol, Miguel, Compañ-Gabucio, Laura, Vaquero-Luna, Jessica, Ruiz-Canela, Miguel, Becerra-Tomás, Nerea, Fitó, Montserrat, Romaguera, Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929461/
https://www.ncbi.nlm.nih.gov/pubmed/31870449
http://dx.doi.org/10.1186/s12966-019-0892-4
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author Galmes-Panades, Aina M.
Varela-Mato, Veronica
Konieczna, Jadwiga
Wärnberg, Julia
Martínez-González, Miguel Ángel
Salas-Salvadó, Jordi
Corella, Dolores
Schröder, Helmut
Vioque, Jesús
Alonso-Gómez, Ángel M.
Martínez, J. Alfredo
Serra-Majem, Luís
Estruch, Ramon
Tinahones, Francisco J.
Lapetra, José
Pintó, Xavier
Tur, Josep A.
Garcia-Rios, Antonio
Riquelme-Gallego, Blanca
Gaforio, José Juan
Matía-Martín, Pilar
Daimiel, Lidia
Micó Pérez, Rafael Manuel
Vidal, Josep
Vázquez, Clotilde
Ros, Emilio
Garcia-Arellano, Ana
Díaz-López, Andrés
Asensio, Eva M.
Castañer, Olga
Fiol, Francisca
Mira-Castejón, Luis Alfredo
Moreno Rodríguez, Anai
Benavente- Marín, Juan Carlos
Abete, Itziar
Tomaino, Laura
Casas, Rosa
Barón López, F. Javier
Fernández-García, José Carlos
Santos-Lozano, José Manuel
Galera, Ana
Mascaró, Catalina M.
Razquin, Cristina
Papandreou, Christopher
Portoles, Olga
Pérez-Vega, Karla Alejandra
Fiol, Miguel
Compañ-Gabucio, Laura
Vaquero-Luna, Jessica
Ruiz-Canela, Miguel
Becerra-Tomás, Nerea
Fitó, Montserrat
Romaguera, Dora
author_facet Galmes-Panades, Aina M.
Varela-Mato, Veronica
Konieczna, Jadwiga
Wärnberg, Julia
Martínez-González, Miguel Ángel
Salas-Salvadó, Jordi
Corella, Dolores
Schröder, Helmut
Vioque, Jesús
Alonso-Gómez, Ángel M.
Martínez, J. Alfredo
Serra-Majem, Luís
Estruch, Ramon
Tinahones, Francisco J.
Lapetra, José
Pintó, Xavier
Tur, Josep A.
Garcia-Rios, Antonio
Riquelme-Gallego, Blanca
Gaforio, José Juan
Matía-Martín, Pilar
Daimiel, Lidia
Micó Pérez, Rafael Manuel
Vidal, Josep
Vázquez, Clotilde
Ros, Emilio
Garcia-Arellano, Ana
Díaz-López, Andrés
Asensio, Eva M.
Castañer, Olga
Fiol, Francisca
Mira-Castejón, Luis Alfredo
Moreno Rodríguez, Anai
Benavente- Marín, Juan Carlos
Abete, Itziar
Tomaino, Laura
Casas, Rosa
Barón López, F. Javier
Fernández-García, José Carlos
Santos-Lozano, José Manuel
Galera, Ana
Mascaró, Catalina M.
Razquin, Cristina
Papandreou, Christopher
Portoles, Olga
Pérez-Vega, Karla Alejandra
Fiol, Miguel
Compañ-Gabucio, Laura
Vaquero-Luna, Jessica
Ruiz-Canela, Miguel
Becerra-Tomás, Nerea
Fitó, Montserrat
Romaguera, Dora
author_sort Galmes-Panades, Aina M.
collection PubMed
description BACKGROUND: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. METHODS: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55–75 years, BMI 27–40 Kg/m(2)) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. RESULTS: Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). CONCLUSIONS: Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. TRIAL REGISTRATION: The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered.
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spelling pubmed-69294612019-12-30 Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study Galmes-Panades, Aina M. Varela-Mato, Veronica Konieczna, Jadwiga Wärnberg, Julia Martínez-González, Miguel Ángel Salas-Salvadó, Jordi Corella, Dolores Schröder, Helmut Vioque, Jesús Alonso-Gómez, Ángel M. Martínez, J. Alfredo Serra-Majem, Luís Estruch, Ramon Tinahones, Francisco J. Lapetra, José Pintó, Xavier Tur, Josep A. Garcia-Rios, Antonio Riquelme-Gallego, Blanca Gaforio, José Juan Matía-Martín, Pilar Daimiel, Lidia Micó Pérez, Rafael Manuel Vidal, Josep Vázquez, Clotilde Ros, Emilio Garcia-Arellano, Ana Díaz-López, Andrés Asensio, Eva M. Castañer, Olga Fiol, Francisca Mira-Castejón, Luis Alfredo Moreno Rodríguez, Anai Benavente- Marín, Juan Carlos Abete, Itziar Tomaino, Laura Casas, Rosa Barón López, F. Javier Fernández-García, José Carlos Santos-Lozano, José Manuel Galera, Ana Mascaró, Catalina M. Razquin, Cristina Papandreou, Christopher Portoles, Olga Pérez-Vega, Karla Alejandra Fiol, Miguel Compañ-Gabucio, Laura Vaquero-Luna, Jessica Ruiz-Canela, Miguel Becerra-Tomás, Nerea Fitó, Montserrat Romaguera, Dora Int J Behav Nutr Phys Act Research BACKGROUND: This study explored the association between inactive time and measures of adiposity, clinical parameters, obesity, type 2 diabetes and metabolic syndrome components. It further examined the impact of reallocating inactive time to time in bed, light physical activity (LPA) or moderate-to-vigorous physical activity (MVPA) on cardio-metabolic risk factors, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. METHODS: This is a cross-sectional analysis of baseline data from 2189 Caucasian men and women (age 55–75 years, BMI 27–40 Kg/m(2)) from the PREDIMED-Plus study (http://www.predimedplus.com/). All participants had ≥3 components of the metabolic syndrome. Inactive time, physical activity and time in bed were objectively determined using triaxial accelerometers GENEActiv during 7 days (ActivInsights Ltd., Kimbolton, United Kingdom). Multiple adjusted linear and logistic regression models were used. Isotemporal substitution regression modelling was performed to assess the relationship of replacing the amount of time spent in one activity for another, on each outcome, including measures of adiposity and body composition, biochemical parameters and blood pressure in older adults. RESULTS: Inactive time was associated with indicators of obesity and the metabolic syndrome. Reallocating 30 min per day of inactive time to 30 min per day of time in bed was associated with lower BMI, waist circumference and glycated hemoglobin (HbA1c) (all p-values < 0.05). Reallocating 30 min per day of inactive time with 30 min per day of LPA or MVPA was associated with lower BMI, waist circumference, total fat, visceral adipose tissue, HbA1c, glucose, triglycerides, and higher body muscle mass and HDL cholesterol (all p-values < 0.05). CONCLUSIONS: Inactive time was associated with a poor cardio-metabolic profile. Isotemporal substitution of inactive time with MVPA and LPA or time in bed could have beneficial impact on cardio-metabolic health. TRIAL REGISTRATION: The trial was registered at the International Standard Randomized Controlled Trial (ISRCTN: http://www.isrctn.com/ISRCTN89898870) with number 89898870 and registration date of 24 July 2014, retrospectively registered. BioMed Central 2019-12-23 /pmc/articles/PMC6929461/ /pubmed/31870449 http://dx.doi.org/10.1186/s12966-019-0892-4 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Galmes-Panades, Aina M.
Varela-Mato, Veronica
Konieczna, Jadwiga
Wärnberg, Julia
Martínez-González, Miguel Ángel
Salas-Salvadó, Jordi
Corella, Dolores
Schröder, Helmut
Vioque, Jesús
Alonso-Gómez, Ángel M.
Martínez, J. Alfredo
Serra-Majem, Luís
Estruch, Ramon
Tinahones, Francisco J.
Lapetra, José
Pintó, Xavier
Tur, Josep A.
Garcia-Rios, Antonio
Riquelme-Gallego, Blanca
Gaforio, José Juan
Matía-Martín, Pilar
Daimiel, Lidia
Micó Pérez, Rafael Manuel
Vidal, Josep
Vázquez, Clotilde
Ros, Emilio
Garcia-Arellano, Ana
Díaz-López, Andrés
Asensio, Eva M.
Castañer, Olga
Fiol, Francisca
Mira-Castejón, Luis Alfredo
Moreno Rodríguez, Anai
Benavente- Marín, Juan Carlos
Abete, Itziar
Tomaino, Laura
Casas, Rosa
Barón López, F. Javier
Fernández-García, José Carlos
Santos-Lozano, José Manuel
Galera, Ana
Mascaró, Catalina M.
Razquin, Cristina
Papandreou, Christopher
Portoles, Olga
Pérez-Vega, Karla Alejandra
Fiol, Miguel
Compañ-Gabucio, Laura
Vaquero-Luna, Jessica
Ruiz-Canela, Miguel
Becerra-Tomás, Nerea
Fitó, Montserrat
Romaguera, Dora
Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title_full Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title_fullStr Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title_full_unstemmed Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title_short Isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the PREDIMED-Plus study
title_sort isotemporal substitution of inactive time with physical activity and time in bed: cross-sectional associations with cardiometabolic health in the predimed-plus study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929461/
https://www.ncbi.nlm.nih.gov/pubmed/31870449
http://dx.doi.org/10.1186/s12966-019-0892-4
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