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Allosteric regulation of protein 14-3-3ζ scaffold by small-molecule editing modulates histone H3 post-translational modifications

Background: Histone post-translational modifications (PTMs) are involved in various biological processes such as transcriptional activation, chromosome packaging, and DNA repair. Previous studies mainly focused on PTMs by directly targeting histone-modifying enzymes such as HDACs and HATs. Methods a...

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Detalles Bibliográficos
Autores principales: Wan, Yan-Jun, Liao, Li-Xi, Liu, Yang, Yang, Heng, Song, Xiao-Min, Wang, Li-Chao, Zhang, Xiao-Wen, Qian, Yi, Liu, Dan, Shi, Xiao-Meng, Han, Li-Wen, Xia, Qing, Liu, Ke-Chun, Du, Zhi-Yong, Jiang, Yong, Zhao, Ming-Bo, Zeng, Ke-Wu, Tu, Peng-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6929985/
https://www.ncbi.nlm.nih.gov/pubmed/31903151
http://dx.doi.org/10.7150/thno.38483

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