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PI3Kα in cardioprotection: Cytoskeleton, late Na(+) current, and mechanism of arrhythmias

PI 3-kinase α (PI3Kα) is a lipid kinase that converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-triphosphate (PIP3). PI3Kα regulates a variety of cellular processes such as nutrient sensing, cell cycle, migration, and others. Heightened activity of PI3Kα in many type...

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Detalles Bibliográficos
Autores principales:	Zhabyeyev, Pavel, Chen, Xueyi, Vanhaesebroeck, Bart, Oudit, Gavin Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930018/ https://www.ncbi.nlm.nih.gov/pubmed/31790629 http://dx.doi.org/10.1080/19336950.2019.1697127

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