Kinetochores attached to microtubule-ends are stabilised by Astrin bound PP1 to ensure proper chromosome segregation

Microtubules segregate chromosomes by attaching to macromolecular kinetochores. Only microtubule-end attached kinetochores can be pulled apart; how these end-on attachments are selectively recognised and stabilised is not known. Using the kinetochore and microtubule-associated protein, Astrin, as a...

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Detalles Bibliográficos
Autores principales: Conti, Duccio, Gul, Parveen, Islam, Asifa, Martín-Durán, José M, Pickersgill, Richard W, Draviam, Viji M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930079/
https://www.ncbi.nlm.nih.gov/pubmed/31808746
http://dx.doi.org/10.7554/eLife.49325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930079/
https://www.ncbi.nlm.nih.gov/pubmed/31808746
http://dx.doi.org/10.7554/eLife.49325

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