Adaptive amino acid substitutions enable transmission of an H9N2 avian influenza virus in guinea pigs

H9N2 is the most prevalent low pathogenic avian influenza virus (LPAIV) in domestic poultry in the world. Two distinct H9N2 poultry lineages, G1-like (A/quail/Hong Kong/G1/97) and Y280-like (A/Duck/Hong Kong/Y280/1997) viruses, are usually associated with binding affinity for both α 2,3 and α 2,6 si...

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Detalles Bibliográficos
Autores principales: Lina, Liu, Saijuan, Chen, Chengyu, Wang, Yuefeng, Lu, Shishan, Dong, Ligong, Chen, Kangkang, Guo, Zhendong, Guo, Jiakai, Li, Jianhui, Zhang, Qingping, Luo, Wenting, Zhang, Yu, Shang, Honglin, Wang, Tengfei, Zhang, Guoyuan, Wen, Jiping, Zhu, Chunmao, Zhang, Meilin, Jin, Yuwei, Gao, Huabin, Shao, Zongzheng, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930279/
https://www.ncbi.nlm.nih.gov/pubmed/31875046
http://dx.doi.org/10.1038/s41598-019-56122-6

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