Cargando…

Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1)

Environmental factors, including substance abuse and stress, cause long-lasting changes in the regulation of gene expression in the brain via epigenetic mechanisms, such as DNA methylation. We examined genome-wide DNA methylation patterns in the prefrontal cortex (PFC, BA10) of 25 pairs of control a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gatta, Eleonora, Grayson, Dennis R., Auta, James, Saudagar, Vikram, Dong, Erbo, Chen, Ying, Krishnan, Harish R., Drnevich, Jenny, Pandey, Subhash C., Guidotti, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930366/ https://www.ncbi.nlm.nih.gov/pubmed/31239533 http://dx.doi.org/10.1038/s41380-019-0449-6

Ejemplares similares

Epigenetic Regulation of GABAergic Neurotransmission and Neurosteroid Biosynthesis in Alcohol Use Disorder
por: Gatta, Eleonora, et al.
Publicado: (2020)

Concordance of Immune-Related Markers in Lymphocytes and Prefrontal Cortex in Schizophrenia
por: Gatta, Eleonora, et al.
Publicado: (2021)

Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABA(A) Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD)
por: Gatta, Eleonora, et al.
Publicado: (2017)

N-Phthalyl-l-Tryptophan (RG108), like Clozapine (CLO), Induces Chromatin Remodeling in Brains of Prenatally Stressed Mice
por: Dong, Erbo, et al.
Publicado: (2019)

Potential role for histone deacetylation in chronic diazepam‐induced downregulation of α1‐GABA(A) receptor subunit expression
por: Auta, James, et al.
Publicado: (2018)

Corticosterone induces discrete epigenetic signatures in the dorsal and ventral hippocampus that depend upon sex and genotype: focus on methylated Nr3c1 gene
por: Caradonna, Salvatore G., et al.
Publicado: (2022)

Dyslexia as an adaptation to cortico-limbic stress system reactivity
por: Kershner, John R.
Publicado: (2020)

Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure
por: Chen, Wei-Yang, et al.
Publicado: (2021)

Cortico-limbic morphology separates tinnitus from tinnitus distress
por: Leaver, Amber M., et al.
Publicado: (2012)

Functional and directed connectivity of the cortico-limbic network in mice in vivo
por: Khastkhodaei, Zeinab, et al.
Publicado: (2021)

Girls' internalizing symptoms and white matter tracts in Cortico-Limbic circuitry
por: Mohamed Ali, Ola, et al.
Publicado: (2018)

Lack of cortico-limbic coupling in bipolar disorder and schizophrenia during emotion regulation
por: Morris, R W, et al.
Publicado: (2012)

Chronic stress disrupts neural coherence between cortico-limbic structures
por: Oliveira, João Filipe, et al.
Publicado: (2013)

Editorial: Decision-making under stress: the importance of cortico-limbic circuits
por: van den Bos, Ruud, et al.
Publicado: (2015)

Neuron-Glia-Immune Triad and Cortico-Limbic System in Pathology of Pain
por: Murray, Isabella, et al.
Publicado: (2021)

Blunted medial prefrontal cortico-limbic reward-related effective connectivity and depression
por: Rupprechter, Samuel, et al.
Publicado: (2020)

Impaired cortico-limbic functional connectivity in schizophrenia patients during emotion processing
por: Comte, Magali, et al.
Publicado: (2017)

Cortico-limbic connectivity changes following fear extinction and relationships with trait anxiety
por: Belleau, Emily L, et al.
Publicado: (2018)

Cortico-limbic disruption, material-specificity, and deficits in cognitive-affective theory of mind
por: Singh, Varsha, et al.
Publicado: (2023)

The Cortico-Limbo-Thalamo-Cortical Circuits: An Update to the Original Papez Circuit of the Human Limbic System
por: Kamali, Arash, et al.
Publicado: (2023)

Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors
por: Matrisciano, Francesco, et al.
Publicado: (2018)

Impaired Limbic Cortico-Striatal Structure and Sustained Visual Attention in a Rodent Model of Schizophrenia
por: Barnes, Samuel A., et al.
Publicado: (2014)

Associations among negative life events, changes in cortico-limbic connectivity, and psychopathology in the ABCD Study
por: Brieant, Alexis E., et al.
Publicado: (2021)

Unraveling the epigenomic and transcriptomic interplay during alcohol-induced anxiolysis
por: Krishnan, Harish R., et al.
Publicado: (2022)

Altered Expression and In Vivo Activity of mGlu5 Variant a Receptors in the Striatum of BTBR Mice: Novel Insights Into the Pathophysiology of Adult Idiopathic Forms of Autism Spectrum Disorders
por: Matrisciano, Francesco, et al.
Publicado: (2022)

An open cortico-basal ganglia loop allows limbic control over motor output via the nigrothalamic pathway
por: Aoki, Sho, et al.
Publicado: (2019)

Integrating cortico-limbic-basal ganglia architectures for learning model-based and model-free navigation strategies
por: Khamassi, Mehdi, et al.
Publicado: (2012)

Sex-dependent effects of early life stress on reinforcement learning and limbic cortico-striatal functional connectivity
por: Zühlsdorff, Katharina, et al.
Publicado: (2022)

Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder
por: Grayson, Dennis R, et al.
Publicado: (2016)

Emotional descriptions increase accidental harm punishment and its cortico-limbic signatures during moral judgment in autism
por: Fittipaldi, Sol, et al.
Publicado: (2023)

Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders
por: Guidotti, Alessandro, et al.
Publicado: (2016)

Sex-dependent sensitivity to positive allosteric modulation of GABA action in an APP knock-in mouse model of Alzheimer's disease: Potential epigenetic regulation
por: Auta, James, et al.
Publicado: (2021)

Resting State Cortico-Limbic Functional Connectivity and Dispositional Use of Emotion Regulation Strategies: A Replication and Extension Study
por: Dörfel, Denise, et al.
Publicado: (2020)

Bidirectional Causal Connectivity in the Cortico-Limbic-Cerebellar Circuit Related to Structural Alterations in First-Episode, Drug-Naive Somatization Disorder
por: Li, Ranran, et al.
Publicado: (2018)

Abnormal Topology of the Structural Connectome in the Limbic Cortico-Basal-Ganglia Circuit and Default-Mode Network Among Primary Insomnia Patients
por: Wu, Yunfan, et al.
Publicado: (2018)

Altered metabolic connectivity within the limbic cortico-striato-thalamo-cortical circuit in presymptomatic and symptomatic behavioral variant frontotemporal dementia
por: Liu, Li, et al.
Publicado: (2023)

High-fat diet-induced obesity and insulin resistance are characterized by differential beta oscillatory signaling of the limbic cortico-basal ganglia loop
por: Maurer, Lukas, et al.
Publicado: (2017)

Asymmetric Interaction of Neuropeptidase Activities between Cortico-Limbic Structures, Plasma and Cardiovascular Function after Unilateral Dopamine Depletions of the Nigrostriatal System
por: Banegas, Inmaculada, et al.
Publicado: (2022)

LRH‐1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance
por: Michalek, Svenja, et al.
Publicado: (2022)

Metabotropic Glutamate 2/3 Receptors and Epigenetic Modifications in Psychotic Disorders: A Review
por: Matrisciano, Francesco, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_t64ghlg030ie9c4pvqhm3mokni