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SFI Enhances Therapeutic Efficiency of Gefitinib: An Insight into Reversal of Resistance to Targeted Therapy in Non-small Cell Lung Cancer Cells
Background: The clinical application of EGFR tyrosine kinase inhibitors is always accompanied by inevitable drug resistance. However, the mechanism remains elusive. In the present study, we investigate the involvement of MAPK/SREBP1 pathway in NSCLC gefitinib resistance and evaluate the synergistic...
Autores principales: | Pan, Zhenzhen, Wang, Kai, Chen, Qiufang, Zheng, Xiulan, Song, Zhengyu, Ding, Xuansheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930422/ https://www.ncbi.nlm.nih.gov/pubmed/31897229 http://dx.doi.org/10.7150/jca.32989 |
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