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Integrin-mediated Signaling via Paxillin-GIT1-PIX Promotes Localized Rac Activation at the Leading Edge and Cell Migration

Rac activation is precisely regulated temporally and spatially by intracellular signaling pathways in migrating cells to guarantee the formation of specific cell protrusions-lamellipodia at the leading edge. Integrins-mediated adhesions also control the signaling pathway for localized Rac activation...

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Detalles Bibliográficos
Autores principales:	Li, Youjun, Wu, Xinzhou, Liu, Zhiqiang, Lu, Kanghui, Liu, Rushi, Guo, Xiangrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930425/ https://www.ncbi.nlm.nih.gov/pubmed/31897230 http://dx.doi.org/10.7150/jca.32853

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