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Downregulation of SPARC Expression Decreases Cell Migration and Invasion Involving Epithelial-Mesenchymal Transition through the p-FAK/p-ERK Pathway in Esophageal Squamous Cell Carcinoma

Purpose: Secreted protein acidic and rich in cysteine (SPARC) is an extracellular glycoprotein overexpressed in various malignancies, including esophageal squamous cell carcinoma (ESCC), and is involved in tumor development and progression. This study was initially designed to investigate the biolog...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Zhang, Yiyin, Da, Jie, Jia, Zhenya, Wu, Hongyang, Gu, Kangsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930426/
https://www.ncbi.nlm.nih.gov/pubmed/31897236
http://dx.doi.org/10.7150/jca.31427