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Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression

The overexpression of ABC transporters induced by anticancer drugs has been found to be the main cause of multidrug resistance. It is actually also a strategy by which cancer cells escape being killed. Tetrandrine is a natural product extracted from the stem of Tinospora crispa. In this study, tetra...

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Detalles Bibliográficos
Autores principales:	Liao, Dan, Zhang, Wei, Gupta, Pranav, Lei, Zi-Ning, Wang, Jing-Quan, Cai, Chao-Yun, Vera, Albert A. De, Zhang, Lei, Chen, Zhe-Sheng, Yang, Dong-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930469/ https://www.ncbi.nlm.nih.gov/pubmed/31801248 http://dx.doi.org/10.3390/molecules24234383

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