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Novel Convenient Approach to the Solid-Phase Synthesis of Oligonucleotide Conjugates

A novel and convenient approach for the solid-phase 5′-functionalization of oligonucleotides is proposed in this article. The approach is based on the activation of free 5′-hydroxyl of polymer support-bound protected oligonucleotides by N,N′-disuccinimidyl carbonate followed by interaction with amin...

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Detalles Bibliográficos
Autores principales:	Meschaninova, Mariya I., Novopashina, Darya S., Semikolenova, Olga A., Silnikov, Vladimir N., Venyaminova, Alya G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930482/ https://www.ncbi.nlm.nih.gov/pubmed/31771111 http://dx.doi.org/10.3390/molecules24234266

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