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Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds

Seaweeds are some of the largest producers of biomass in the marine environment and are rich in bioactive compounds that are often used for human and animal health. Porphyran and carrageenan are natural compounds derived from red seaweeds. The former is a characteristic polysaccharide of Porphyra, w...

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Autores principales: Liu, Zhiwei, Gao, Tianheng, Yang, Ying, Meng, Fanxin, Zhan, Fengping, Jiang, Qichen, Sun, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930528/
https://www.ncbi.nlm.nih.gov/pubmed/31775255
http://dx.doi.org/10.3390/molecules24234286
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author Liu, Zhiwei
Gao, Tianheng
Yang, Ying
Meng, Fanxin
Zhan, Fengping
Jiang, Qichen
Sun, Xian
author_facet Liu, Zhiwei
Gao, Tianheng
Yang, Ying
Meng, Fanxin
Zhan, Fengping
Jiang, Qichen
Sun, Xian
author_sort Liu, Zhiwei
collection PubMed
description Seaweeds are some of the largest producers of biomass in the marine environment and are rich in bioactive compounds that are often used for human and animal health. Porphyran and carrageenan are natural compounds derived from red seaweeds. The former is a characteristic polysaccharide of Porphyra, while the latter is well known from Chondrus, Gigartina, and various Eucheuma species, all in Rhodophyceae. The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and therefore deemed as potential chemotherapeutic or chemopreventive agents. This review attempts to review the current study of anti-cancer activity and the possible mechanisms of porphyran and carrageenan derived from red seaweeds to various cancers, and their cooperative actions with other anti-cancer chemotherapeutic agents is also discussed.
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spelling pubmed-69305282019-12-26 Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds Liu, Zhiwei Gao, Tianheng Yang, Ying Meng, Fanxin Zhan, Fengping Jiang, Qichen Sun, Xian Molecules Review Seaweeds are some of the largest producers of biomass in the marine environment and are rich in bioactive compounds that are often used for human and animal health. Porphyran and carrageenan are natural compounds derived from red seaweeds. The former is a characteristic polysaccharide of Porphyra, while the latter is well known from Chondrus, Gigartina, and various Eucheuma species, all in Rhodophyceae. The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and therefore deemed as potential chemotherapeutic or chemopreventive agents. This review attempts to review the current study of anti-cancer activity and the possible mechanisms of porphyran and carrageenan derived from red seaweeds to various cancers, and their cooperative actions with other anti-cancer chemotherapeutic agents is also discussed. MDPI 2019-11-25 /pmc/articles/PMC6930528/ /pubmed/31775255 http://dx.doi.org/10.3390/molecules24234286 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Zhiwei
Gao, Tianheng
Yang, Ying
Meng, Fanxin
Zhan, Fengping
Jiang, Qichen
Sun, Xian
Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title_full Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title_fullStr Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title_full_unstemmed Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title_short Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds
title_sort anti-cancer activity of porphyran and carrageenan from red seaweeds
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930528/
https://www.ncbi.nlm.nih.gov/pubmed/31775255
http://dx.doi.org/10.3390/molecules24234286
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