Deficiency of Urokinase Plasminogen Activator May Impair β Cells Regeneration and Insulin Secretion in Type 2 Diabetes Mellitus

Background: The relationship between urokinase-type plasminogen activator (uPA) and the development of type 2 diabetes mellitus (T2DM) was investigated in the study by using mice and cell models, as well as patients with T2DM. Methods: In mice models, wild-type and uPA knockout (uPA-/-) BALB/c mice...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Ze, Ou, Shih-Hsiang, Chang, Li-Chien, Lin, Yuh-Feng, Pei, Dee, Chen, Jin-Shuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930534/
https://www.ncbi.nlm.nih.gov/pubmed/31756973
http://dx.doi.org/10.3390/molecules24234208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930534/
https://www.ncbi.nlm.nih.gov/pubmed/31756973
http://dx.doi.org/10.3390/molecules24234208

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