Late-Stage Copper-Catalyzed Radiofluorination of an Arylboronic Ester Derivative of Atorvastatin

There is an unmet need for late-stage (18)F-fluorination strategies to label molecules with a wide range of relevant functionalities to medicinal chemistry, in particular (hetero)arenes, aiming to obtain unique in vivo information on the pharmacokinetics/pharmacodynamics (PK/PD) using positron emiss...

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Detalles Bibliográficos
Autores principales: S. Clemente, Gonçalo, Zarganes-Tzitzikas, Tryfon, Dömling, Alexander, H. Elsinga, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930542/
https://www.ncbi.nlm.nih.gov/pubmed/31756986
http://dx.doi.org/10.3390/molecules24234210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930542/
https://www.ncbi.nlm.nih.gov/pubmed/31756986
http://dx.doi.org/10.3390/molecules24234210

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