Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer

This study aims to investigate the anticancer effect of Oroxin B (OB) both in vitro and in vivo, and the molecular mechanism involved in microRNA-221 and the PI3K/Akt/PTEN pathway through modulation of apoptosis in Hepatocellular carcinoma (HCC). DEN-induced rats and HepG2 cells based on the microfl...

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Detalles Bibliográficos
Autores principales: Li, Nannan, Men, Wenxiao, Zheng, Yibo, Wang, Hechen, Meng, Xiansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930563/
https://www.ncbi.nlm.nih.gov/pubmed/31801250
http://dx.doi.org/10.3390/molecules24234384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930563/
https://www.ncbi.nlm.nih.gov/pubmed/31801250
http://dx.doi.org/10.3390/molecules24234384

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