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Discovery of Selective Butyrylcholinesterase (BChE) Inhibitors through a Combination of Computational Studies and Biological Evaluations

As there are increased levels and activity of butyrylcholiesterase (BChE) in the late stage of Alzheimer’s disease (AD), development of selective BChE inhibitors is of vital importance. In this study, a workflow combining computational technologies and biological assays were implemented to identify...

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Detalles Bibliográficos
Autores principales:	Zhou, You, Lu, Xin, Yang, Hongyu, Chen, Yao, Wang, Feng, Li, Jifu, Tang, Zhiran, Cheng, Xifei, Yang, Yingbin, Xu, Li, Xia, Qingyou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930573/ https://www.ncbi.nlm.nih.gov/pubmed/31757047 http://dx.doi.org/10.3390/molecules24234217

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