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Concepts and Core Principles of Fragment-Based Drug Design

In this review, a general introduction to fragment-based drug design and the underlying concepts is given. General considerations and methodologies ranging from library selection/construction over biophysical screening and evaluation methods to in-depth hit qualification and subsequent optimization...

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Detalles Bibliográficos
Autores principales:	Kirsch, Philine, Hartman, Alwin M., Hirsch, Anna K. H., Empting, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930586/ https://www.ncbi.nlm.nih.gov/pubmed/31779114 http://dx.doi.org/10.3390/molecules24234309

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