Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2C11 Enzymes in Rat Liver Microsomes: In Vitro Inhibitory Effect of Salicylic Acid on CYP2C11 Enzyme

The inhibitory effect of new chemical entities on rat liver P450 marker activities was investigated in a functional approach towards drug development. Treatment of colorectal cancer (CRC) and chemoprevention using salicylic acid has gained a lot of attention, mainly in the prevention of the onset of...

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Detalles Bibliográficos
Autores principales: Salhab, Hassan, Naughton, Declan P., Barker, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930622/
https://www.ncbi.nlm.nih.gov/pubmed/31775347
http://dx.doi.org/10.3390/molecules24234294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930622/
https://www.ncbi.nlm.nih.gov/pubmed/31775347
http://dx.doi.org/10.3390/molecules24234294

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