Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles

An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.

Detalles Bibliográficos
Autores principales: Dai, Zeshu, Tian, Qingqiang, Li, Yanwu, Shang, Suqin, Luo, Wen, Wang, Xuetong, Li, Dan, Zhang, Ying, Li, Zhiyao, Yuan, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930643/
https://www.ncbi.nlm.nih.gov/pubmed/31757097
http://dx.doi.org/10.3390/molecules24234224
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author Dai, Zeshu
Tian, Qingqiang
Li, Yanwu
Shang, Suqin
Luo, Wen
Wang, Xuetong
Li, Dan
Zhang, Ying
Li, Zhiyao
Yuan, Jianyong
author_facet Dai, Zeshu
Tian, Qingqiang
Li, Yanwu
Shang, Suqin
Luo, Wen
Wang, Xuetong
Li, Dan
Zhang, Ying
Li, Zhiyao
Yuan, Jianyong
author_sort Dai, Zeshu
collection PubMed
description An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.
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spelling pubmed-69306432019-12-26 Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles Dai, Zeshu Tian, Qingqiang Li, Yanwu Shang, Suqin Luo, Wen Wang, Xuetong Li, Dan Zhang, Ying Li, Zhiyao Yuan, Jianyong Molecules Article An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures. MDPI 2019-11-20 /pmc/articles/PMC6930643/ /pubmed/31757097 http://dx.doi.org/10.3390/molecules24234224 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dai, Zeshu
Tian, Qingqiang
Li, Yanwu
Shang, Suqin
Luo, Wen
Wang, Xuetong
Li, Dan
Zhang, Ying
Li, Zhiyao
Yuan, Jianyong
Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title_full Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title_fullStr Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title_full_unstemmed Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title_short Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles
title_sort michael addition reaction catalyzed by imidazolium chloride to protect amino groups and construct medium ring heterocycles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930643/
https://www.ncbi.nlm.nih.gov/pubmed/31757097
http://dx.doi.org/10.3390/molecules24234224
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