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Development of Targeted Alpha Particle Therapy for Solid Tumors
Targeted alpha-particle therapy (TAT) aims to selectively deliver radionuclides emitting α-particles (cytotoxic payload) to tumors by chelation to monoclonal antibodies, peptides or small molecules that recognize tumor-associated antigens or cell-surface receptors. Because of the high linear energy...
Autores principales: | Tafreshi, Narges K., Doligalski, Michael L., Tichacek, Christopher J., Pandya, Darpan N., Budzevich, Mikalai M., El-Haddad, Ghassan, Khushalani, Nikhil I., Moros, Eduardo G., McLaughlin, Mark L., Wadas, Thaddeus J., Morse, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930656/ https://www.ncbi.nlm.nih.gov/pubmed/31779154 http://dx.doi.org/10.3390/molecules24234314 |
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