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Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein

Autoimmune diseases are caused by uncontrolled endogenous immune responses against healthy cells. They may develop due to an impaired function of regulatory T cells (Tregs), which normally suppress self-specific effector immune cells. Interleukin 2 (IL-2) and tumor necrosis factor (TNF) have been id...

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Detalles Bibliográficos
Autores principales:	Padutsch, Tanja, Sendetski, Maksim, Huber, Carina, Peters, Nathalie, Pfizenmaier, Klaus, Bethea, John R., Kontermann, Roland E., Fischer, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930692/ https://www.ncbi.nlm.nih.gov/pubmed/31920671 http://dx.doi.org/10.3389/fphar.2019.01490

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