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Osteochondral Tissue Chip Derived From iPSCs: Modeling OA Pathologies and Testing Drugs
Osteoarthritis (OA) is a chronic disease mainly characterized by degenerative changes in cartilage, but other joint elements such as bone are also affected. To date, there are no disease-modifying OA drugs (DMOADs), owing in part to a deficiency of current models in simulating OA pathologies and eti...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930794/ https://www.ncbi.nlm.nih.gov/pubmed/31921815 http://dx.doi.org/10.3389/fbioe.2019.00411 |