α-Synuclein Strains Target Distinct Brain Regions and Cell Types

The clinical and pathological differences between synucleinopathies such as Parkinson’s disease and multiple system atrophy have been postulated to stem from unique strains of α-synuclein aggregates, akin to what occurs in prion diseases. Here, we demonstrate that inoculation of transgenic mice with...

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Detalles Bibliográficos
Autores principales: Lau, Angus, So, Raphaella W.L., Lau, Heather H.C., Sang, Jason C., Ruiz-Riquelme, Alejandro, Fleck, Shelaine C., Stuart, Erica, Menon, Sindhu, Visanji, Naomi P., Meisl, Georg, Faidi, Rania, Marano, Maria M., Schmitt-Ulms, Cian, Wang, Zhilan, Fraser, Paul E., Tandon, Anurag, Hyman, Bradley T., Wille, Holger, Ingelsson, Martin, Klenerman, David, Watts, Joel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930851/
https://www.ncbi.nlm.nih.gov/pubmed/31792467
http://dx.doi.org/10.1038/s41593-019-0541-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930851/
https://www.ncbi.nlm.nih.gov/pubmed/31792467
http://dx.doi.org/10.1038/s41593-019-0541-x

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