Performance of the SAEM and FOCEI Algorithms in the Open‐Source, Nonlinear Mixed Effect Modeling Tool nlmixr

The free and open‐source package nlmixr implements pharmacometric nonlinear mixed effects model parameter estimation in R. It provides a uniform language to define pharmacometric models using ordinary differential equations. Performances of the stochastic approximation expectation‐maximization (SAEM...

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Detalles Bibliográficos
Autores principales: Schoemaker, Rik, Fidler, Matthew, Laveille, Christian, Wilkins, Justin J., Hooijmaijers, Richard, Post, Teun M., Trame, Mirjam N., Xiong, Yuan, Wang, Wenping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930853/
https://www.ncbi.nlm.nih.gov/pubmed/31654482
http://dx.doi.org/10.1002/psp4.12471

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