A Citrulline‐Based Translational Population System Toxicology Model for Gastrointestinal‐Related Adverse Events Associated With Anticancer Treatments

Gastrointestinal (GI)‐related adverse events (AEs) are commonly observed in the clinic during cancer treatments. Citrulline is a potentially translatable biomarker of GI AEs. In this study, irinotecan‐induced citrulline changes were studied for a range of doses and schedules in rats. A translational...

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Detalles Bibliográficos
Autores principales: Yoneyama, Tomoki, Abdul‐Hadi, Kojo, Brown, Adam, Guan, Emily, Wagoner, Matt, Zhu, Andy Z.X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930863/
https://www.ncbi.nlm.nih.gov/pubmed/31671257
http://dx.doi.org/10.1002/psp4.12475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930863/
https://www.ncbi.nlm.nih.gov/pubmed/31671257
http://dx.doi.org/10.1002/psp4.12475

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